Jensen Ackles and Jared Padalecki played brothers Dean and Sam Winchester for 15 years on "Supernatural." A journey so long would presumably establish firm grounds for a real-life bromance, as it has for Ackles and Padalecki. "I love Jensen deeply. He's my brother — he has been for many years, and he always will be, no matter what," Padalecki told The New York Times after "Supernatural" concluded. Ackles, meanwhile, has acknowledged that the relationship he shares with Padalecki is "pretty rare and may or may not ever happen again." 

Both Texas natives, Ackles and Padalecki have been by each other's sides through interviews, comic conventions, and photoshoots for what seems like ages. In fact, each took on the role as groomsman at the other's wedding, per PopSugar. The brotherly pair, along with their "Supernatural" dad Jeffrey Dean Morgan, also have matching crown tattoos and dub themselves the "three kings" (via Entertainment Weekly). 

Come June 2021, the Ackles-Padalecki bromance appeared to hit an unprecedented snag. When news broke that a "Supernatural" prequel, helmed by Ackles, was in the works at CW, Padalecki tweeted that he was "gutted" at having had no knowledge about it. Such hell broke loose on social media — there were threats involved, per TVLine — that only the Winchesters could have contained it, which they ultimately did. Padalecki, in another tweet, said he'd had a talk with Ackles and that "things are good."